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AKC Canine Health Foundation Alert

Broad Institute Call for Samples [Tuesday, October 8, 2007]

Nearly two years ago, researchers announced they had successfully decoded
the genome of the domestic dog. Now, an international team of researchers let by
the Dog Disease Research Group at the Broad Institute of MIT and Harvard, and
supported in part by the AKC Canine Health Foundation, has used the genome to
find genes for two dog traits, the ridge in Rhodesian Ridgeback and Thai
Ridgeback dogs and white coat color in Boxers and Bull Terriers. These studies
were just published in Nature Genetics. The scientists are now turning their
attention to complex diseases that often involve multiple genetic and
environmental causes, such as cancers and autoimmune disease. Their goal is to
understand - and ultimately treat - these diseases in dogs as well as their
human companions.

To be successful, the scientists at the Broad Institute urgently need the
help of purebred dog breeders and owners. For each disease studied, blood
samples from hundreds of affected dogs and older, healthy controls are required.
This research can only be done with blood samples (DNA from cheek swabs is not
high enough quality). They can only use DNA from purebred dogs, but do not need
close family members. The blood can been drawn by your vet and sent to the Broad
Institute Dog Disease Research Group in Cambridge, Massachusetts.

Read more about this call for samples
here<http://sdm3.rm04.net/ctt?kn=2&m=1037011&r=NzUyOTU5MDcxNwS2&b=0&j=MzM5NjQ4MD\
AS1&mt=1>.

Help us "Raise the Bar" this year through your Annual Fund Contribution.
Click here to contribute to research studies funded by the AKC Canine Health
Foundation<http://sdm3.rm04.net/ctt?kn=8&m=1037011&r=NzUyOTU5MDcxNwS2&b=0&j=MzM5\
NjQ4MDAS1&mt=1>.


Contact:
Jeff Sossamon
Director of Development & Communications
AKC Canine Health Foundation
PO Box 37941
Raleigh, NC 27627-7941
(919) 334-4015 (b)
(919) 334-4011 (f)
(888) 682-9696 (toll free)
jds@...<mailto:jds@...>

www.akcchf.org<http://sdm3.rm04.net/ctt?kn=4&m=1037011&r=NzUyOTU5MDcxNwS2&b=0&j=\
MzM5NjQ4MDAS1&mt=1>

The AKC Canine Health Foundation, founded in 1995 by the American Kennel
Club, is the largest nonprofit worldwide to fund health research exclusively for
canines. Our goal is to help dogs live longer, healthier lives. The AKC Canine
Health Foundation is the leader in non-invasive genetic health research, stem
cell research, and biotherapeutics benefiting both canines and humans. Through
the generous financial support of the American Kennel Club and the Nestlé Purina
PetCare Co., we're proud to announce we have allocated more than $18 million in
canine health research through 74 schools and research institutions worldwide


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